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Articles
(43 articles)
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Arch. Pharm. Pharm. Med. Chem. 2003, 2, 95–103 Substituted Quinazolines, Part 2. Synthesis and In-Vitro Anticancer Evaluation ofNew 2-Substituted Mercapto-3H-quinazoline Analogs Ashraf A. Khalil, Sami G. Abdel Hamide, Abdulrahman M. Al-Obaid,Hussein I. El-Subbagh Department...
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Saudi Pharmaceutical Journal, Vol. 13, No. 1 January 2005 ROLE OF MOLYBDENUM HYDROXYLASES IN DISEASES Mohamed A. Al-Omar*1, Hussein I. El-Subbagh1, Christine Beedham2, John Smith3 1Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457,...
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Bioorganic & Medicinal Chemistry 13 (2005) 4929–4935. Lewis acid-promoted transformation of 2-alkoxy-pyridines into 2-aminopyridines and their antibacterial activity. Part 2: Remarkably facile C–N bond formation. Alaa A.-M. Abdel-Aziz,a,* Hussein I. El-Subbaghb and...
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Arch. Pharm. Chem. Life Sci. 2005, 338, 175−180. Synthesis and In Vitro Antioxidant Activity of someNew Fused Pyridine AnalogsMohamed A. Al-Omara, Khairia M. Youssefa, Magda A. El-Sherbenya, Sit. Albanat A. Awadallab, Hussein I. El-Subbagha aDepartment of Pharmaceutical Chemistry,...
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SYNTHESIS AND INVESTIGATION OF NOVEL SHELF-STABLE,BRAIN-SPECIFIC CHEMICAL DELIVERY SYSTEM Abdulrahman M. Al-Obaid, Hassan A. Farag, Ashraf A. Khalil,Othman A. Al-Shabanah, Sami G. Abdel Hamide, Hassan A. El-Kashef,Hassan S. Ahmed, Ahmed M. Al-Affifi, Elrasheed A. Gadkariem,...
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J. Med. Chem. 2006, 49, 760-769Dopamine/Serotonin Receptor Ligands. 10:1 SAR Studies on Azecine-type Dopamine ReceptorLigands by Functional Screening at Human Cloned D1, D2L, and D5 Receptors with a Microplate Reader Based Calcium Assay Lead to a Novel Potent D1/D5 Selective...
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Bioorganic & Medicinal Chemistry 14 (2006) 8608–8621 Synthesis, dihydrofolate reductase inhibition, antitumortesting, and molecular modeling study of some new4(3H)-quinazolinone analogs Sarah T. Al-Rashood,a Ihsan A. Aboldahab,a Mahmoud N. Nagi,b Laila A. Abouzeid,a Alaa...
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Resveratrol (RSVL) is a naturally occurring polyphenolic stilbene with striking structural similarity to the estrogen receptor (ER) agonist diethylstilbestrol (DES). However, in estrogen-responsive biological systems, RSVL behaved as a mixed agonist/antagonist ligand. The molecular basis of such...
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Molecular modelling is a collective term that refers to theoretical methods and computational techniques to model or mimic the behaviour of molecules. The techniques are used in the fields of computational chemistry, computational biology and materials science for studying molecular systems...
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a][1,3]diazepin-4), as a member of a new generation of ultra-short acting hypnotics is4 exhibited potent in-vivo activity with a very rapid onset of action and ain-vivo and in-vitro metabolic profile of 4 is also described. Urine was pooled4 was incubated with rat-liver microsomal and...
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